SCHEMBL24679904

SCHEMBL24679904

Nc1ncnc2c1ncn2[C@@H]1C[C@@H]2COP(=O)(S)O[C@@H]3C[C@@H](COP(=O)(S)OC[C@H]21)O[C@H]3n1cnc2c(N)ncnc21

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21263824 0.92 STING1 (0.53) STING1
SCHEMBL24680634 0.87 STING1 (0.66) STING1
SCHEMBL22349194 0.86 STING1 (0.65) STING1
SCHEMBL20691397 0.86 STING1 (0.65) STING1
SCHEMBL20692277 0.86 STING1 (0.65) STING1
SCHEMBL21263968 0.86 STING1 (0.48) STING1
SCHEMBL24680564 0.84 STING1 (0.63) STING1
SCHEMBL20692070 0.84 STING1 (0.72) STING1
SCHEMBL20691371 0.84 STING1 (0.72) STING1
SCHEMBL20691401 0.84 STING1 (0.73) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658565-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-11-09 — — EP disclosed
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