Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462569 | 0.88 | PPARA (0.47) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL6885083 | 0.85 | PPARA (0.52) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL2463840 | 0.81 | PPARG (0.43) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4755223 | 0.80 | PPARA (0.53) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4754216 | 0.79 | PPARA (0.48) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL6885086 | 0.79 | PPARA (0.53) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4752401 | 0.78 | PPARG (0.49) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL12732409 | 0.76 | PPARG (0.58) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL12732408 | 0.74 | PPARA (0.51) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL1765900 | 0.74 | PPARD (0.66) | PPARGPPARAPPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |