Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.72 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.72 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677118 | 0.91 | S1PR1 (0.87) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1874061 | 0.90 | S1PR1 (0.81) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL676614 | 0.90 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1875727 | 0.88 | S1PR1 (0.87) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL676636 | 0.87 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1869687 | 0.84 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL676623 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL16143976 | 0.83 | S1PR1 (0.73) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL16143828 | 0.83 | S1PR1 (0.68) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1878527 | 0.82 | S1PR1 (0.68) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371811-A2 | Azetidinecarboxylic acid derivative and medicinal use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-05 | — | — | EP | disclosed |