Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | PI4KA | P42356 | 3/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224919 | 0.84 | ADORA2A (0.49) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL9343605 | 0.82 | ADORA2A (0.67) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL9343603 | 0.82 | ADORA2A (0.67) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL21636982 | 0.81 | ADCY5 (0.66) | ADCY5ADORA2AADORA1DNPH1PRKAB2 | |
| SCHEMBL21263838 | 0.81 | ADCY5 (0.43) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL20434932 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL20434928 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL24465167 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2AADORA1ADORA3PI4KA | |
| SCHEMBL24059865 | 0.78 | POLB (0.73) | ADORA1ENPP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL20277576 | 0.78 | POLB (0.73) | ADORA1ENPP1DNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |