Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20433160 | 0.83 | ATR (0.82) | ATR | |
| SCHEMBL20433172 | 0.82 | ATR (0.79) | ATR | |
| SCHEMBL20433111 | 0.78 | ATR (0.81) | ATR | |
| SCHEMBL24680979 | 0.75 | ATR (0.81) | ATR | |
| SCHEMBL20433164 | 0.75 | ATR (0.55) | ATR | |
| SCHEMBL2484829 | 0.74 | ATR (1.00) | ATR | |
| SCHEMBL20433043 | 0.73 | ATR (0.55) | ATR | |
| SCHEMBL20433183 | 0.73 | ATR (0.65) | ATR | |
| SCHEMBL13137938 | 0.72 | ATR (1.00) | ATR | |
| SCHEMBL20432939 | 0.72 | ATR (0.81) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059932-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2022-09-21 | — | — | EP | disclosed |