Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800064 | 1.00 | MAPK8 (0.39) | MAPK8MAPK10HCAR2SLC6A2SLC6A4 | |
| SCHEMBL24683203 | 0.88 | HSP90AA1 (0.39) | ALDH1A1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL29799821 | 0.88 | HSP90AA1 (0.39) | ALDH1A1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL30664739 | 0.86 | MAPT (0.33) | ALDH1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24683893 | 0.86 | MAPT (0.33) | ALDH1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24683860 | 0.85 | HSP90AA1 (0.36) | ALDH1A1LMNAKMT2AHSP90AA1HSP90B1 | |
| SCHEMBL29799884 | 0.85 | HSP90AA1 (0.36) | ALDH1A1LMNAKMT2AHSP90AA1HSP90B1 | |
| SCHEMBL24683861 | 0.85 | HSP90AA1 (0.40) | KDM4ELMNAHSP90AA1HSP90B1 | |
| SCHEMBL30664663 | 0.85 | HSP90AA1 (0.40) | KDM4ELMNAHSP90AA1HSP90B1 | |
| SCHEMBL24682815 | 0.85 | HSP90AA1 (0.39) | ALDH1A1KDM4EMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |