Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948443 | 0.83 | TAAR1 (0.50) | TAAR1GAAHTTCYP2A13NPSR1 | |
| SCHEMBL7030193 | 0.83 | TAAR1 (0.43) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL3612078 | 0.83 | TAAR1 (0.68) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL3040407 | 0.82 | TAAR1 (0.61) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL601569 | 0.79 | TAAR1 (0.63) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL28596017 | 0.79 | TAAR1 (0.63) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL30776827 | 0.79 | TAAR1 (0.63) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL17552700 | 0.77 | TAAR1 (0.61) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL113076 | 0.77 | TAAR1 (0.73) | TAAR1GAAHTTBACE1KDM4E | |
| SCHEMBL5884187 | 0.77 | TAAR1 (0.61) | TAAR1GAAHTTBACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237903-A1 | QUINAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-11-17 | — | — | WO | disclosed |