Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229081 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686268 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL19380534 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686939 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686927 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687310 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687409 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24686941 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL24687404 | 1.00 | HPGD (0.63) | HPGDSMN1; SMN2HTTPTGS1PTGS2 | |
| SCHEMBL15025739 | 0.96 | HPGD (0.57) | HPGDSMN1; SMN2HTTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173421-A1 | MODULATION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY | SEAGEN INC. | 2024-05-30 | — | — | US | disclosed |
| EP-4326333-A1 | MODULATION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY | Seagen Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022226100-A1 | MODULATION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY | SEAGEN INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022226100-A1 | MODULATION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY | SEAGEN INC. (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240173421-A1 | MODULATION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY | CD47, CD2, SSB | HPGD 3900/4885SMN1; SMN2 1081/4885HTT 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.