Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 6/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687256 | 0.89 | KCNJ5 (0.47) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL24685943 | 0.89 | P2RX4 (0.48) | KCNJ5KCNJ3P2RX4MEN1KMT2A | |
| SCHEMBL24686054 | 0.87 | P2RX4 (0.58) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL29852253 | 0.87 | P2RX4 (0.58) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL24686674 | 0.87 | KCNJ5 (0.54) | KCNJ5KCNJ3KCNJ6P2RX4MAOB | |
| SCHEMBL24685910 | 0.87 | KCNJ5 (0.50) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL24686639 | 0.87 | KCNJ5 (0.55) | KCNJ5KCNJ3KCNJ6ALDH1A1P2RX4 | |
| SCHEMBL24686678 | 0.86 | KCNH2 (0.49) | KCNJ5KCNJ3P2RX4MAOB | |
| SCHEMBL24687281 | 0.86 | KCNJ5 (0.46) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 | |
| SCHEMBL24686619 | 0.84 | P2RX4 (0.46) | KCNJ5KCNJ3KCNJ6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |