Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.60 |
| ▸ | JAK3 | P52333 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688026 | 0.94 | EGFR (0.64) | EGFRJAK3 | |
| SCHEMBL24687690 | 0.91 | EGFR (0.62) | EGFRJAK3 | |
| SCHEMBL24688036 | 0.90 | EGFR (0.60) | EGFRJAK3 | |
| SCHEMBL24688025 | 0.89 | EGFR (0.66) | EGFRJAK3 | |
| SCHEMBL24687699 | 0.88 | EGFR (0.57) | EGFRJAK3 | |
| SCHEMBL24687685 | 0.86 | EGFR (0.63) | EGFR | |
| SCHEMBL24687812 | 0.86 | EGFR (0.74) | EGFR | |
| SCHEMBL24687462 | 0.85 | EGFR (0.57) | EGFRJAK3 | |
| SCHEMBL24687827 | 0.85 | EGFR (0.65) | EGFRJAK3 | |
| SCHEMBL24687689 | 0.84 | EGFR (0.58) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212538-A1 | DIAZEPANONE-FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | BLUEPRINT MEDICINES CORPORATION (US) | 2022-10-06 | — | — | WO | disclosed |