Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688561 | 0.86 | ESRRG (0.51) | DRD4MAPTMEN1KMT2AGFER | |
| SCHEMBL24688549 | 0.86 | CDK4 (0.50) | DRD4DRD2MAPTMEN1KMT2A | |
| SCHEMBL24688558 | 0.79 | ESRRG (0.47) | MAPTALDH1A1CDK4CCND1 | |
| SCHEMBL24688808 | 0.77 | ESRRG (0.50) | DRD2MAPTMEN1KMT2AHTR1A | |
| SCHEMBL24688550 | 0.77 | ESRRG (0.52) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL24688916 | 0.76 | ESRRG (0.49) | MAPTALDH1A1 | |
| SCHEMBL24688547 | 0.76 | ESRRG (0.49) | MAPTCDK4CCND1 | |
| SCHEMBL24688929 | 0.76 | ESRRG (0.51) | MAPTALDH1A1CDK4CCND1 | |
| SCHEMBL29968359 | 0.72 | ESRRG (0.57) | MAPTALDH1A1 | |
| SCHEMBL24688546 | 0.72 | ESRRG (0.67) | MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245124-A1 | NOVEL ETHENE COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2022-11-24 | — | — | WO | disclosed |