Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 11/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | ESRRB | O95718 | 6/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688916 | 0.86 | ESRRG (0.49) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688558 | 0.83 | ESRRG (0.47) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688929 | 0.81 | ESRRG (0.51) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688561 | 0.81 | ESRRG (0.51) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688808 | 0.77 | ESRRG (0.50) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688546 | 0.76 | ESRRG (0.67) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688913 | 0.75 | ESRRG (0.57) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688559 | 0.74 | ESRRG (0.64) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688923 | 0.73 | ESRRG (0.65) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688547 | 0.73 | ESRRG (0.49) | ESRRGESR1KCNH2ESRRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245124-A1 | NOVEL ETHENE COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2022-11-24 | — | — | WO | disclosed |