Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | CYCS | P99999 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12451489 | 0.96 | ABCG2 (0.52) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12392069 | 0.96 | ABCG2 (0.52) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL17688989 | 0.95 | ABCG2 (0.50) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL24689574 | 0.95 | ABCG2 (0.50) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL24689530 | 0.94 | ABCG2 (0.43) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12451490 | 0.93 | ABCG2 (0.48) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL17688986 | 0.93 | ABCG2 (0.48) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12392075 | 0.93 | ABCG2 (0.48) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12450828 | 0.91 | ABCG2 (0.45) | ABCG2TOP1CYCSMAPTSMN1; SMN2 | |
| SCHEMBL12392100 | 0.91 | ABCG2 (0.45) | ABCG2TOP1CYCSMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459955-B1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBERATUNGS II AG (AT) | 2022-11-02 | — | — | EP | disclosed |