Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465273 | 0.91 | S1PR1 (0.35) | S1PR1S1PR3LMNA | |
| SCHEMBL2464358 | 0.89 | S1PR1 (0.47) | S1PR1S1PR3S1PR5MITFTP53 | |
| SCHEMBL2456141 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3S1PR5FFAR4 | |
| SCHEMBL2460745 | 0.82 | S1PR1 (0.46) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3462797 | 0.81 | S1PR1 (0.38) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2458635 | 0.81 | S1PR1 (0.42) | S1PR1S1PR3 | |
| SCHEMBL2459880 | 0.81 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2467232 | 0.80 | S1PR1 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2474869 | 0.80 | S1PR1 (0.38) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2456198 | 0.80 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366702-A1 | New oxadiazole derivatives | Almirall, S.A. (ES) | 2011-09-21 | — | — | EP | claimed |
| EP-2366702-A1 | New oxadiazole derivatives | Almirall, S.A. (ES) | 2011-09-21 | — | — | EP | disclosed |