Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696054 | 0.99 | HPGD (0.65) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24696337 | 0.86 | HPGD (0.50) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24696061 | 0.86 | HPGD (0.60) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24696332 | 0.85 | HPGD (0.49) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24695825 | 0.85 | HPGD (0.61) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24696062 | 0.83 | HPGD (0.44) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24696338 | 0.82 | HPGD (0.46) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24695986 | 0.82 | HPGD (0.91) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24695989 | 0.82 | HPGD (0.91) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24695837 | 0.82 | HPGD (0.91) | HPGDGAASMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |