Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695643 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24696342 | 0.99 | KDM4E (0.38) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24695812 | 0.97 | KDM4E (0.38) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24696144 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24695640 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24696001 | 0.92 | KDM4E (0.38) | SMN1; SMN2ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL24695818 | 0.92 | KDM4E (0.38) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24696033 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB | |
| SCHEMBL24696386 | 0.91 | KDM4E (0.38) | SMN1; SMN2ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL24695601 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2FAAHALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |