Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696390 | 0.92 | HPGD (0.34) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696051 | 0.91 | HPGD (0.33) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696053 | 0.88 | HPGD (0.34) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695956 | 0.87 | HPGD (0.33) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696221 | 0.86 | CNR2 (0.38) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695954 | 0.85 | HPGD (0.34) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696160 | 0.85 | CNR2 (0.37) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696155 | 0.82 | HPGD (0.45) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695988 | 0.82 | HPGD (0.45) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696348 | 0.82 | KDM4E (0.40) | HPGDALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |