Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695773 | 0.99 | CNR2 (0.37) | CNR2HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL24696389 | 0.93 | CNR2 (0.36) | CNR2HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL24696160 | 0.93 | CNR2 (0.37) | CNR2HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL24696219 | 0.92 | CNR2 (0.36) | CNR2HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL24696221 | 0.92 | CNR2 (0.38) | CNR2HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL24696262 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695679 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695771 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24695589 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24696216 | 0.87 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |