Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696052 | 0.99 | HPGD (0.42) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696220 | 0.97 | HPGD (0.43) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696035 | 0.93 | HPGD (0.44) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696213 | 0.93 | HPGD (0.44) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696255 | 0.89 | HPGD (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696260 | 0.89 | HPGD (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24695686 | 0.89 | HPGD (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24696039 | 0.89 | HPGD (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24695685 | 0.89 | HPGD (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL24695587 | 0.84 | HPGD (0.44) | HPGDGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |