Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695982 | 0.87 | HPGD (0.48) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24695796 | 0.85 | HPGD (0.48) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24696338 | 0.84 | HPGD (0.46) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24696274 | 0.84 | HPGD (0.46) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24696155 | 0.83 | HPGD (0.45) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24695988 | 0.83 | HPGD (0.45) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24696154 | 0.83 | HPGD (0.45) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24695797 | 0.83 | HPGD (0.45) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24695588 | 0.82 | HPGD (0.72) | HPGDALDH1A1HSD17B10POLBBLM | |
| SCHEMBL24696226 | 0.82 | HPGD (0.59) | HPGDALDH1A1HSD17B10POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |