Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696368 | 0.99 | KDM4E (0.40) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24695974 | 0.90 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24696344 | 0.89 | KDM4E (0.38) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24695642 | 0.87 | KDM4E (0.38) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24696353 | 0.86 | KDM4E (0.42) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24696124 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24696376 | 0.85 | KDM4E (0.41) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24696358 | 0.85 | KDM4E (0.43) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24695814 | 0.85 | HPGD (0.41) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL24695832 | 0.84 | KDM4E (0.37) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |