Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696356 | 0.99 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10KMT2AP2RY14 | |
| SCHEMBL24695613 | 0.89 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10KMT2AP2RY14 | |
| SCHEMBL24696323 | 0.89 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10KMT2AP2RY14 | |
| SCHEMBL24696215 | 0.89 | HPGD (0.48) | KDM4EALDH1A1HSD17B10KMT2ACASP1 | |
| SCHEMBL24696036 | 0.89 | HPGD (0.48) | KDM4EALDH1A1HSD17B10KMT2ACASP1 | |
| SCHEMBL24696355 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL24696348 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10KMT2AP2RY14 | |
| SCHEMBL24696352 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL24696322 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10KMT2AP2RY14 | |
| SCHEMBL24695982 | 0.81 | HPGD (0.48) | KDM4EALDH1A1HSD17B10KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |