Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696143 | 1.00 | P2RY14 (0.37) | P2RY14KDM4EALDH1A1HTR6L3MBTL1 | |
| SCHEMBL24696341 | 0.99 | KDM4E (0.37) | P2RY14KDM4EALDH1A1HTR6L3MBTL1 | |
| SCHEMBL24696372 | 0.90 | KDM4E (0.36) | P2RY14KDM4EALDH1A1HTR6L3MBTL1 | |
| SCHEMBL24696260 | 0.87 | HPGD (0.46) | KDM4EALDH1A1L3MBTL1GAAPOLB | |
| SCHEMBL24696375 | 0.87 | SMN1; SMN2 (0.40) | KDM4EALDH1A1HTR6POLBKMT2A | |
| SCHEMBL24696145 | 0.87 | SMN1; SMN2 (0.40) | KDM4EALDH1A1HTR6POLBKMT2A | |
| SCHEMBL24696039 | 0.87 | HPGD (0.46) | KDM4EALDH1A1L3MBTL1GAAPOLB | |
| SCHEMBL24695686 | 0.87 | HPGD (0.46) | KDM4EALDH1A1L3MBTL1GAAPOLB | |
| SCHEMBL24696255 | 0.87 | HPGD (0.46) | KDM4EALDH1A1L3MBTL1GAAPOLB | |
| SCHEMBL24695685 | 0.87 | HPGD (0.46) | KDM4EALDH1A1L3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |