Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.54 |
| ▸ | WIZ | O95785 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22536038 | 1.00 | CRBN (0.57) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL25087626 | 0.94 | CRBN (0.61) | CRBNIKZF2WIZ | |
| SCHEMBL26299161 | 0.90 | CRBN (0.60) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL24789294 | 0.88 | IKZF2 (0.52) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL29648417 | 0.87 | CRBN (0.62) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL29648275 | 0.87 | CRBN (0.62) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL24696747 | 0.87 | CRBN (0.62) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL24501550 | 0.87 | CRBN (0.62) | CRBNMAPTIKZF2WIZ | |
| SCHEMBL23267660 | 0.86 | CRBN (0.62) | CRBNIKZF2WIZ | |
| SCHEMBL25988439 | 0.85 | CRBN (0.70) | CRBNIKZF2WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253250-A1 | BRUTON'S TYROSINE KINASE DEGRADER CONTAINING FUSED-RING OR SPIRO-RING | 正大天晴药业集团股份有限公司 | 2022-12-08 | — | — | WO | disclosed |