SCHEMBL24697100

SCHEMBL24697100

CC1=CCC(C)CC(F)C1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14536429 0.77
SCHEMBL720412 0.72
SCHEMBL22590926 0.68 TSHR (0.30) TSHRMAPK1
SCHEMBL18513556 0.68
SCHEMBL719090 0.66
SCHEMBL14923094 0.64 TSHR (0.31) TSHRMAPK1
SCHEMBL27790205 0.64 TSHR (0.31) TSHRMAPK1
SCHEMBL28256445 0.64 TSHR (0.34) TSHRMAPK1
SCHEMBL27425062 0.64 TSHR (0.31) TSHRMAPK1
SCHEMBL27453912 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022170060-A1 COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH VERASTEM, INC. (US) 2022-08-11 WO disclosed