Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698708 | 0.80 | — | — | |
| SCHEMBL27115227 | 0.68 | HTR2A (0.45) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL856157 | 0.66 | CYP1A2 (0.44) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL4899939 | 0.63 | HTR2A (0.38) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL22574603 | 0.62 | KMT2A (0.38) | HTR2AHTR2CHTR2BCYP1A2CYP2C9 | |
| SCHEMBL25403539 | 0.61 | PDE10A (0.39) | HTR2AHTR2CHTR2BCYP1A2CYP2C9 | |
| SCHEMBL857098 | 0.61 | KMT2A (0.46) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL26660095 | 0.61 | KMT2A (0.49) | HTR2AHTR2CHTR2BCYP1A2CYP2C19 | |
| SCHEMBL75623 | 0.60 | PDE10A (0.41) | HTR2AHTR2CHTR2BCYP1A2CYP2C9 | |
| SCHEMBL22175059 | 0.60 | HTR2A (0.43) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |