Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | PPARD | Q03181 | 10/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467674 | 0.91 | PPARD (0.48) | PPARAPPARDPPARGRAB9ALMNA | |
| SCHEMBL2465769 | 0.88 | PPARD (0.46) | PPARAPPARDPPARGTP53MAPT | |
| SCHEMBL2466281 | 0.88 | PPARA (0.45) | PPARAPPARDPPARGSMN1; SMN2LMNA | |
| SCHEMBL2465693 | 0.86 | PPARD (0.50) | PPARAPPARDPPARGALDH1A1MAPT | |
| SCHEMBL4755245 | 0.85 | SMN1; SMN2 (0.38) | PPARAPPARDPPARGSMN1; SMN2NPC1 | |
| SCHEMBL24656237 | 0.85 | PPARD (0.39) | PPARAPPARDPPARGSMN1; SMN2NPC1 | |
| SCHEMBL30003495 | 0.85 | PPARD (0.39) | PPARAPPARDPPARGSMN1; SMN2NPC1 | |
| SCHEMBL1765907 | 0.84 | PPARD (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4809536 | 0.84 | PPARD (0.37) | PPARAPPARDPPARGSMN1; SMN2NPC1 | |
| SCHEMBL12732429 | 0.84 | PPARD (0.42) | PPARAPPARDPPARGSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |