SCHEMBL24699321

SCHEMBL24699321

CCCN(OCCNC(=O)OC(C)(C)C)C(=O)C1=Cc2ccc(C(=O)OC)cc2N=C(N)C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.48
▸ TLR7 Q9NYK1 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24699322 0.94 TLR8 (0.49) TLR8TLR7
SCHEMBL24699665 0.93 TLR8 (0.49) TLR8TLR7
SCHEMBL24699259 0.93 TLR8 (0.51) TLR8TLR7
SCHEMBL24507866 0.89 TLR8 (0.44) TLR8TLR7
SCHEMBL24699261 0.89 TLR8 (0.64) TLR8TLR7
SCHEMBL24698694 0.89 TLR8 (0.65) TLR8TLR7
SCHEMBL30945301 0.88 TLR8 (0.44) TLR8TLR7
SCHEMBL24699320 0.88 TLR8 (0.63) TLR8TLR7
SCHEMBL24699266 0.88 TLR8 (0.45) TLR8TLR7
SCHEMBL31051347 0.88 TLR8 (0.45) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117769439-A 2-amino-4-carboxamide-benzazepine immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-03-26 — — CN disclosed
WO-2022204536-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-09-29 — — WO disclosed
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