SCHEMBL2470037 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	S1PR1	P21453	8/20	0.33

▸	HSD11B1	P28845	1/20	0.33

▸	HDAC1	Q13547	1/20	0.33

▸	HDAC8	Q9BY41	1/20	0.33

▸	HDAC6	Q9UBN7	1/20	0.33

▸	PSEN1	P49768	1/20	0.33

▸	PSEN2	P49810	1/20	0.33

▸	APH1B	Q8WW43	1/20	0.33

▸	NCSTN	Q92542	1/20	0.33

▸	APH1A	Q96BI3	1/20	0.33

▸	PSENEN	Q9NZ42	1/20	0.33

▸	S1PR3	Q99500	4/20	0.32

▸	GABRA1	P14867	2/20	0.32

▸	MAPT	P10636	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2472055	0.95	S1PR1 (0.36)	S1PR1HSD11B1HDAC1HDAC8HDAC6
SCHEMBL2474330	0.93	S1PR1 (0.34)	S1PR1S1PR3MAPT
SCHEMBL2472586	0.84	S1PR1 (0.44)	S1PR1HDAC1HDAC6S1PR3
SCHEMBL2470503	0.82	S1PR1 (0.38)	S1PR1S1PR3MAPT
SCHEMBL2470619	0.80	S1PR1 (0.32)	S1PR1S1PR3MAPT
SCHEMBL2469504	0.80	S1PR1 (0.41)	S1PR1S1PR3MAPT
SCHEMBL3463743	0.79	S1PR1 (0.38)	S1PR1S1PR3
SCHEMBL2473761	0.79	S1PR1 (0.49)	S1PR1S1PR3MAPT
SCHEMBL2831128	0.79	S1PR1 (0.39)	S1PR1S1PR3MAPT
SCHEMBL2474869	0.79	S1PR1 (0.38)	S1PR1S1PR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2370431-A1	1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE	Almirall S.A. (ES)	2011-10-05	—	—	EP	claimed
WO-2010072352-A1	1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE	ALMIRALL S.A. (ES)	2010-07-01	—	—	WO	claimed