SCHEMBL24700758

SCHEMBL24700758

C=C(/C=C\CN1CCCC[C@H]1CO)CCC#N

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3442047 0.73 HRH3 (0.40) TERT
SCHEMBL2845040 0.72 POLB (0.40) TERT
SCHEMBL2845038 0.72 POLB (0.40) TERT
SCHEMBL11219569 0.69 POLB (0.37) TERT
SCHEMBL3893332 0.69 CFB (0.38) TERT
SCHEMBL3442502 0.68 HRH3 (0.43)
SCHEMBL10687905 0.68 HRH3 (0.43)
SCHEMBL3442503 0.68 HRH3 (0.43)
SCHEMBL3442674 0.65 SPHK2 (0.43)
SCHEMBL3442670 0.65 SPHK2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4046988-A1 2-FORMYL-3-HYDROXYPHENYLOXYMETHYL COMPOUNDS CAPABLE OF MODULATING HEMOGLOBIN Global Blood Therapeutics, Inc. (US) 2022-08-24 EP disclosed