SCHEMBL2470087

SCHEMBL2470087

O=C(NCCC1CC1)Oc1ccc(N2CCN(C(=O)c3ccccc3F)CC2)nn1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 13/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471523 0.91 SCD (0.75) SCD
SCHEMBL2466037 0.90 SCD (0.56) SCD
SCHEMBL2470065 0.89 SCD (0.73) SCD
SCHEMBL2470623 0.89 SCD (0.61) SCD
SCHEMBL2466295 0.87 SCD (0.52) SCD
SCHEMBL2470127 0.87 SCD (0.53) SCD
SCHEMBL2469460 0.87 SCD (0.53) SCD
SCHEMBL2467882 0.86 SCD (0.69) SCD
SCHEMBL2466639 0.85 SCD (0.51) SCD
SCHEMBL2464906 0.84 SCD (0.74) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1648874-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2011-10-05 EP claimed