SCHEMBL24700899

SCHEMBL24700899

CC(C)(C)c1nc(Nc2cccc(C(F)(F)F)c2)nc(Nc2cccc(C(F)(F)F)c2)n1

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDH2 P48735 11/20 0.75
MAPT P10636 3/20 0.66
LMNA P02545 2/20 0.66
MAPK1 P28482 1/20 0.63
APP P05067 3/20 0.61
AURKA O14965 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27256168 0.93 IDH2 (0.66) IDH2MAPTLMNAMAPK1APP
SCHEMBL30568833 0.86 IDH2 (1.00) IDH2MAPTLMNAMAPK1APP
SCHEMBL4544808 0.83 IDH2 (0.77) IDH2MAPTLMNAMAPK1APP
SCHEMBL28455381 0.82 IDH2 (0.91) IDH2MAPTLMNAMAPK1APP
SCHEMBL1391617 0.81 IDH2 (0.64) IDH2MAPTLMNAMAPK1APP
SCHEMBL30568865 0.81 MAPT (0.83) IDH2MAPTLMNAMAPK1APP
SCHEMBL23666319 0.81 IDH2 (0.73) IDH2MAPTLMNAMAPK1APP
SCHEMBL30568857 0.81 IDH2 (1.00) IDH2MAPTLMNAMAPK1APP
SCHEMBL1391440 0.79 MAPT (1.00) IDH2MAPTLMNAMAPK1APP
SCHEMBL28458395 0.79 IDH2 (0.86) IDH2MAPTLMNAMAPK1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220332970-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-10-20 US disclosed