SCHEMBL247011

SCHEMBL247011

COC(=O)c1ccccn1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.68
MAPT P10636 3/20 0.68
POLB P06746 1/20 0.68
PKM P14618 3/20 0.62
ALDH1A1 P00352 5/20 0.61
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
LMNA P02545 2/20 0.57
NAPRT Q6XQN6 1/20 0.57
P4HTM Q9NXG6 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 6/20 0.56
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
MAPK1 P28482 1/20 0.53
HPGD P15428 1/20 0.53
CDK5 Q00535 1/20 0.53
PAX8 Q06710 1/20 0.53
CDK5R1 Q15078 1/20 0.53
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30166417 1.00 KDM4E (0.68) KDM4EMAPTPOLBPKMALDH1A1
SCHEMBL29576494 1.00 KDM4E (0.68) KDM4EMAPTPOLBPKMALDH1A1
Hydrochloric Acid SCHEMBL30779106 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Water SCHEMBL27868581 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Fluoride SCHEMBL28136311 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Hydrochloric Acid SCHEMBL30827488 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Hydrochloric Acid SCHEMBL9500180 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Bromide SCHEMBL27426373 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Hydrochloric Acid SCHEMBL4430906 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1
Hydrochloric Acid SCHEMBL27837788 0.98 KDM4E (0.66) KDM4EMAPTPOLBPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616674-B2 Anti-fibrotic NEU3 inhibitor compounds and methods of use THE TEXAS A&M UNIVERSITY SYSTEM (US) 2026-05-05 US claimed
CN-120023024-A Combined collecting agent for lead-zinc sulfide ore flotation separation and application thereof 昆明理工大学 2025-05-23 CN claimed
WO-2025078932-A1 A PROCESS FOR SELECTIVE DIMETHYL CARBONATE (DMC) SYNTHESIS AND A SYSTEM THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2025-04-17 WO claimed
WO-2025078933-A1 A PROCESS FOR SELECTIVE DIMETHYL CARBONATE (DMC) SYNTHESIS AND A SYSTEM THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2025-04-17 WO claimed
CN-118201925-A Macrocyclic compounds and methods of making the same 詹森生物科技公司 2024-06-14 CN claimed
CN-116396213-B Preparation method of 2-methyl picolinate 济南大学 2024-06-14 CN claimed
CN-117618423-A Inhibitors of tryptophan dioxygenase (IDO 1 and TDO) and their use in therapy 奥克兰联合服务有限公司 2024-03-01 CN claimed
CN-117599049-A Inhibitors of tryptophan dioxygenase (IDO 1 and TDO) and their use in therapy 奥克兰联合服务有限公司 2024-02-27 CN claimed
CN-114479008-B Demulsifier and preparation method and application thereof 中国石油化工股份有限公司 2024-01-26 CN claimed
EP-4308560-A1 PRO DRUGS OF PDE10 COMPOUNDS Merck Sharp & Dohme LLC (US) 2024-01-24 EP claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998050342-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-12 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
US-5256626-A Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds MONSANTO COMPANY (US) 1993-10-26 US claimed
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US claimed
EP-0097551-B1 USE OF VANADIUM, NIOBIUM AND TANTALUM PEROXIDIC COMPLEXES AS REAGENTS AND CATALYSTS IN THE HYDROXYLATION OF AROMATIC HYDROCARBONS Institut Français du Pétrole (FR) 1986-10-15 EP claimed
US-4529824-A Vanadium, niobium or tanatlum peroxidic complex INSTITUT FRANCAIS DU PETROLE (FR) 1985-07-16 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed