Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998591 | 0.79 | — | — | |
| SCHEMBL432248 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| SCHEMBL48375 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| SCHEMBL6802 | 0.76 | — | — | |
| SCHEMBL1703765 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| Hydrochloric Acid SCHEMBL481915 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL19610866 | 0.73 | PLG (0.52) | PLGPLATLMNANCF1 | |
| Hydrochloric Acid SCHEMBL25254209 | 0.73 | PLG (0.52) | PLGPLATLMNANCF1 | |
| Ammonia Solution, Strong SCHEMBL1313037 | 0.73 | — | — | |
| Cyclohexane SCHEMBL5461183 | 0.70 | PLG (0.50) | PLGPLATLMNANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396587-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396587-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | MCL1, BCL2A1, BCL2L1 | PLG 3723/4885PLAT 4076/4885LMNA 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.