Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 14/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460743 | 0.89 | S1PR1 (0.57) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL2470835 | 0.88 | S1PR1 (0.53) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13262937 | 0.85 | HDAC4 (0.40) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2456198 | 0.83 | S1PR1 (0.38) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL2473902 | 0.82 | S1PR1 (0.36) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL2472095 | 0.80 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL2469504 | 0.79 | S1PR1 (0.41) | S1PR1S1PR3 | |
| SCHEMBL2474869 | 0.79 | S1PR1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL2474311 | 0.78 | NPC1 (0.39) | S1PR1S1PR3 | |
| SCHEMBL2458148 | 0.78 | S1PR1 (0.37) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370431-A1 | 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | Almirall S.A. (ES) | 2011-10-05 | — | — | EP | claimed |
| WO-2010072352-A1 | 1, 2, 4 -OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2010-07-01 | — | — | WO | claimed |