⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245323 | 0.69 | — | — | |
| SCHEMBL3019277 | 0.67 | — | — | |
| SCHEMBL8694480 | 0.67 | — | — | |
| SCHEMBL7703514 | 0.65 | — | — | |
| SCHEMBL12474043 | 0.63 | — | — | |
| SCHEMBL12922722 | 0.63 | — | — | |
| SCHEMBL11903245 | 0.63 | — | — | |
| SCHEMBL592904 | 0.63 | — | — | |
| SCHEMBL788930 | 0.62 | — | — | |
| SCHEMBL6696867 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248663-A | 5- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) -5-azaspiro [2.5] octane-8-carboxylic acid derivatives as novel JAK kinase inhibitors | 利奥制药有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-110062761-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and their use as GLUN2B receptor modulators | 詹森药业有限公司 | 2019-07-26 | — | — | CN | claimed |
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | claimed |
| CN-103732596-B | Pyrrolopyrimidine derivatives | NOVARTIS AG (CH) | 2016-06-01 | — | — | CN | claimed |
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | claimed |
| CN-103153945-B | 1-oximino-3-phenyl-propanes | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | claimed |
| CN-103415507-B | As the 3-amino-pyridine class of GPBAR1 agonist | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | claimed |
| CN-105358148-A | LOSMAPIMOD for use in treating glomerular disease | GLAXOSMITHKLINE IP NO 2 LTD | 2016-02-24 | — | — | CN | claimed |
| CN-103124729-B | As the pharmaceutical active compounds of Axl inhibitor | LEAD DISCOVERY CENTER GMBH (DE) | 2016-01-20 | — | — | CN | claimed |
| CN-103768044-B | Suppress the application of the reactive compound of DJ-1 dimerization | ZHEJIANG UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103772299-A | Novel piperazine amide derivatives | HOFFMANN LA ROCHE | 2014-05-07 | — | — | CN | claimed |
| CN-103732596-A | Novel pyrrolopyrimidine derivatives | NOVARTIS AG | 2014-04-16 | — | — | CN | claimed |
| CN-103442712-A | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI SA | 2013-12-11 | — | — | CN | claimed |
| CN-103415507-A | 3-amino-pyridines as GPBAR1 agonists | HOFFMANN LA ROCHE | 2013-11-27 | — | — | CN | claimed |
| CN-101600700-B | Novel 2-amino oxazolines as TAAR1 ligands for CNS disorders | HOFFMANN LA ROCHE | 2013-08-21 | — | — | CN | claimed |
| CN-103153945-A | 1-oximino-3-phenyl-propanes | HOFFMANN LA ROCHE | 2013-06-12 | — | — | CN | claimed |
| CN-101528713-B | Pyridazine derivatives as inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 | HOFFMANN LA ROCHE | 2013-05-22 | — | — | CN | claimed |
| CN-101287734-B | 2-amino-7, 8-dihydro-6H-pyrido [4,3-d ] pyrimidin-5-ones | NOVARTIS AG | 2011-07-20 | — | — | CN | claimed |
| CN-101983191-A | Oxim derivatives as hsp90 inhibitors | TAKEDA PHARMACEUTICAL | 2011-03-02 | — | — | CN | claimed |
| CN-101287734-A | 2-amino-7, 8-dihydro-6H-pyrido [4, 3-d ] pyrimidin-5-ones | NOVARTIS AG (CH) | 2008-10-15 | — | — | CN | claimed |