Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.38 |
| ▸ | CNR2 | P34972 | 15/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742966 | 0.89 | CNR1 (0.37) | CNR1CNR2KDM4E | |
| SCHEMBL1742605 | 0.89 | CNR1 (0.37) | CNR1CNR2KDM4E | |
| SCHEMBL14454992 | 0.85 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL1744305 | 0.82 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL1743837 | 0.79 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL1742969 | 0.77 | CNR1 (0.38) | CNR1CNR2KDM4E | |
| SCHEMBL1742613 | 0.77 | CNR1 (0.38) | CNR1CNR2KDM4E | |
| SCHEMBL12161254 | 0.76 | CNR1 (0.35) | CNR1CNR2KDM4E | |
| SCHEMBL2610807 | 0.76 | CA12 (0.34) | CNR1CNR2 | |
| SCHEMBL16299276 | 0.76 | CA12 (0.34) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371827-A1 | Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use | SANOFI (FR) | 2011-10-05 | — | — | EP | disclosed |