SCHEMBL24712019

SCHEMBL24712019

NC1CCN(S(=O)(=O)C2CC(F)(F)C2)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68733 0.79 EPHX2 (0.42) SMYD3
Hydrochloric Acid SCHEMBL27034982 0.77 EPHX2 (0.41) SMYD3
SCHEMBL14115748 0.75 EPHX2 (0.47) SMYD3
SCHEMBL31443396 0.70 CHRNA7 (0.32)
SCHEMBL932571 0.69 CA1 (0.50)
Trifluoroacetic Acid SCHEMBL29191931 0.69 EPHX2 (0.40) SMYD3
SCHEMBL24572139 0.68 CHRNA7 (0.33)
SCHEMBL23270095 0.67 EPHX2 (0.36) SMYD3
SCHEMBL363726 0.66 TP53 (0.48)
SCHEMBL1517111 0.65 EPHX2 (0.46) SMYD3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022258023-A1 COMPOUND AS CDK KINASE INHIBITOR AND USE THEREOF 郑州同源康医药有限公司 2022-12-15 WO disclosed