Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443778 | 0.85 | KDM4E (0.31) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL24329608 | 0.75 | CYP2D6 (0.34) | HRH3KDM4EALDH1A1MAPTPKM | |
| SCHEMBL9963424 | 0.73 | DRD3 (0.49) | DRD3HRH3KCNH2 | |
| SCHEMBL12563450 | 0.70 | PIK3CA (0.30) | — | |
| SCHEMBL11921171 | 0.69 | HRH3 (0.37) | HRH3KDM4EALDH1A1KCNH2 | |
| SCHEMBL25121973 | 0.66 | HRH4 (0.30) | — | |
| SCHEMBL21946763 | 0.63 | GRM5 (0.31) | — | |
| SCHEMBL24732180 | 0.63 | SOS1 (0.33) | HRH3 | |
| SCHEMBL24730771 | 0.62 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24711527 | 0.62 | MAOB (0.31) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |