SCHEMBL24713835

SCHEMBL24713835

C=CC(=O)N1CC(Oc2cc3c(Nc4cc(-c5cccc(C(F)(F)F)c5F)ccc4OC)ncnc3cc2OC)C1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 20/20 0.69
ERBB2 P04626 9/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032256 1.00 EGFR (0.69) EGFRERBB2
SCHEMBL30030554 0.94 EGFR (0.69) EGFRERBB2
SCHEMBL24713880 0.94 EGFR (0.69) EGFRERBB2
SCHEMBL30031749 0.92 EGFR (0.73) EGFRERBB2
SCHEMBL24714878 0.92 EGFR (0.73) EGFRERBB2
SCHEMBL24714588 0.90 EGFR (0.82) EGFRERBB2
SCHEMBL30031975 0.90 EGFR (0.82) EGFRERBB2
SCHEMBL24713836 0.89 EGFR (0.55) EGFRERBB2
SCHEMBL30979938 0.89 EGFR (0.71) EGFRERBB2
SCHEMBL24715164 0.89 EGFR (0.71) EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4328222-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF Voronoi Inc. (KR) 2024-02-28 EP claimed
EP-4328222-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF Voronoi Inc. (KR) 2024-02-28 EP disclosed
EP-4328222-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF Voronoi Inc. (KR) 2024-02-28 EP disclosed
WO-2022225238-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF 보로노이 주식회사 2022-10-27 WO disclosed