Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.53 |
| ▸ | TEC | P42680 | 1/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.53 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.53 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031287 | 1.00 | EGFR (0.62) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL24715222 | 0.96 | EGFR (0.67) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL30032313 | 0.96 | EGFR (0.67) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL24714060 | 0.92 | EGFR (0.64) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL30031301 | 0.92 | EGFR (0.64) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL27141272 | 0.91 | EGFR (0.62) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL24714501 | 0.91 | EGFR (0.61) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL30979929 | 0.89 | EGFR (0.68) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL24714489 | 0.89 | EGFR (0.68) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL27136452 | 0.89 | EGFR (0.68) | EGFRERBB2RIPK2RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | claimed |
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |