Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24716881 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL15746865 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL23458178 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL3511572 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL16604796 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL16604806 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL17314784 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL17314782 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL2737895 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2USP2RECQLNPC1HSD17B10 | |
| SCHEMBL15561495 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2USP2RECQLNPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120450-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022221642-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |