Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.61 |
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626606 | 1.00 | NQO2 (0.61) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL23015612 | 0.77 | NQO2 (1.00) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL30275436 | 0.75 | NQO2 (0.64) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL24715739 | 0.75 | NQO2 (0.64) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL6678542 | 0.74 | NQO2 (0.65) | NQO2CYP19A1ARHPGDALDH1A1 | |
| SCHEMBL6676714 | 0.73 | AR (0.50) | NQO2CYP19A1ARHPGDALDH1A1 | |
| SCHEMBL6682273 | 0.71 | NQO2 (0.44) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL6677205 | 0.70 | AR (0.41) | NQO2CYP19A1ARMAPTHPGD | |
| SCHEMBL6671371 | 0.70 | NQO2 (0.56) | NQO2CYP19A1MAPTHPGDALDH1A1 | |
| SCHEMBL13480899 | 0.70 | AR (0.50) | ARMAPTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |