⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23517174 | 0.77 | — | — | |
| SCHEMBL19832147 | 0.74 | — | — | |
| SCHEMBL7071831 | 0.69 | — | — | |
| SCHEMBL11666694 | 0.67 | — | — | |
| SCHEMBL616847 | 0.67 | — | — | |
| SCHEMBL1719639 | 0.65 | — | — | |
| SCHEMBL16091165 | 0.65 | — | — | |
| SCHEMBL28721585 | 0.63 | — | — | |
| SCHEMBL11585908 | 0.63 | — | — | |
| SCHEMBL1805609 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472303-B1 | GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE | JANSSEN BIOTECH INC (US) | 2022-12-14 | — | — | EP | disclosed |