Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 15/20 | 0.41 |
| ▸ | CA2 | P00918 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722998 | 0.87 | BLM (0.38) | BLMPMP22HSD17B10MRGPRX4KDM4E | |
| SCHEMBL29892650 | 0.86 | KDM4E (0.48) | BLMPMP22MRGPRX4KDM4EALOX15 | |
| SCHEMBL2349945 | 0.86 | KDM4E (0.48) | BLMPMP22MRGPRX4KDM4EALOX15 | |
| SCHEMBL30960193 | 0.85 | KDM4E (0.47) | BLMPMP22MRGPRX4KDM4EALOX15 | |
| SCHEMBL15865623 | 0.85 | KDM4E (0.47) | BLMPMP22MRGPRX4KDM4EALOX15 | |
| SCHEMBL31679405 | 0.85 | MRGPRX4 (0.40) | BLMPMP22HSD17B10MRGPRX4KDM4E | |
| SCHEMBL23568184 | 0.84 | KDM4E (0.50) | MRGPRX4KDM4EALOX15TSHRACMSD | |
| SCHEMBL24627236 | 0.84 | MRGPRX4 (0.41) | BLMPMP22HSD17B10MRGPRX4KDM4E | |
| SCHEMBL31156712 | 0.84 | MRGPRX4 (0.41) | BLMPMP22HSD17B10MRGPRX4KDM4E | |
| SCHEMBL12453251 | 0.83 | KDM4E (0.46) | MRGPRX4KDM4EALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232943-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-11-10 | — | — | WO | disclosed |