SCHEMBL2472307

SCHEMBL2472307

COC1CCCc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.68
GID4 Q8IVV7 1/20 0.49
GPR84 Q9NQS5 1/20 0.45
HTT P42858 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC6A4 P31645 1/20 0.44
PDPK1 O15530 1/20 0.43
FFAR1 O14842 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12727345 1.00 IDO1 (0.68) IDO1GID4GPR84HTTMEN1
SCHEMBL31251494 1.00 IDO1 (0.68) IDO1GID4GPR84HTTMEN1
SCHEMBL29518873 1.00 IDO1 (0.68) IDO1GID4GPR84HTTMEN1
SCHEMBL3907558 1.00 IDO1 (0.68) IDO1GID4GPR84HTTMEN1
SCHEMBL9720722 0.89 IDO1 (0.55) IDO1HTTMEN1KMT2A
SCHEMBL14209228 0.88 IDO1 (0.66) IDO1GPR84PDPK1
SCHEMBL447420 0.88 IDO1 (0.66) IDO1GPR84PDPK1
SCHEMBL21300294 0.88 IDO1 (0.66) IDO1GPR84PDPK1
SCHEMBL15330041 0.84 IDO1 (0.72) IDO1GID4GPR84HTTSLC6A4
SCHEMBL180403 0.84 IDO1 (0.72) IDO1GID4GPR84HTTSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014086697-A1 SUBSTITUTED THIAZOLE COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2014-06-12 WO claimed
WO-2025229494-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-11-06 WO disclosed
CN-113395993-B Heterocyclic compounds and their use 武田药品工业株式会社 2024-02-20 CN disclosed
EP-4217502-A1 ENGINEERED BIOCATALYSTS AND METHODS FOR SYNTHESIZING CHIRAL AMINES Codexis, Inc. (US) 2023-08-02 EP disclosed
CN-112374969-B Application of supported noble metal catalyst in selective hydrogenation reaction of naphthalene derivative 沈阳化工研究院有限公司 2023-01-24 CN disclosed
CN-112374968-B Application of supported catalyst in selective hydrogenation reaction of naphthalene derivatives 沈阳化工研究院有限公司 2022-07-26 CN disclosed
WO-2022066534-A1 ENGINEERED BIOCATALYSTS AND METHODS FOR SYNTHESIZING CHIRAL AMINES CODEXIS, INC. (US) 2022-03-31 WO disclosed
CN-112374969-A Application of supported noble metal catalyst in selective hydrogenation reaction of naphthalene derivative 沈阳化工研究院有限公司 2021-02-19 CN disclosed
CN-112374968-A Application of supported catalyst in selective hydrogenation reaction of naphthalene derivative 沈阳化工研究院有限公司 2021-02-19 CN disclosed
CN-211383858-U 6-methoxy-1-tetralone production preparation distillation plant 武汉海昕药物研究有限公司 2020-09-01 CN disclosed
US-4638001-A ANTISECRETORY, ANTIULCER AGENTS WILLIAM H. RORER, INC. (US) 1987-01-20 US disclosed
EP-0074903-B1 DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE, THEIR PREPARATION AND THEIR THERAPEUTIC USE SYNTHELABO (FR) 1986-11-05 EP disclosed
US-4604404-A Antiviral sulfonated naphthalene formaldehyde condensation polymers A. H. ROBINS COMPANY, INC. (US) 1986-08-05 US disclosed
US-4588719-A ANTISCERETORY AGENTS, ANTIULCER AGENTS WILLIAM H. RORER, INC. (US) 1986-05-13 US disclosed
EP-0150192-A4 BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. RORER INTERNAT OVERSEAS INC (US) 1985-09-16 EP disclosed
EP-0150192-A1 BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. RORER INT OVERSEAS (US) 1985-08-07 EP disclosed
US-4529723-A Gastrointestinal disorders; antiulcer agents WILLIAM H. RORER, INC. (US) 1985-07-16 US disclosed
WO-1984004247-A1 BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES RORER INT OVERSEAS (US) 1984-11-08 WO disclosed
EP-0105984-A1 Aromatic formaldehyde condensation polymers as dental plaque barriers Johnson & Johnson Products Inc. (US) 1984-04-25 EP disclosed
US-4361547-A PERIODIC APPLICATION TO TEETH JOHNSON & JOHNSON PRODUCTS, INC. (US) 1982-11-30 US disclosed