Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381461 | 0.88 | CYP17A1 (0.52) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL16330300 | 0.85 | CYP17A1 (0.54) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL13827424 | 0.82 | HDAC8 (0.48) | CYP17A1HDAC8 | |
| SCHEMBL26079062 | 0.80 | CYP17A1 (0.39) | CYP17A1MAPK14NAMPTPSMB8 | |
| SCHEMBL26079041 | 0.80 | HDAC8 (0.46) | CYP17A1MAPK14NAMPTPSMB8PPARG | |
| SCHEMBL12677009 | 0.80 | CYP17A1 (0.58) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL16246084 | 0.80 | CYP17A1 (0.58) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL27493682 | 0.80 | CYP17A1 (0.58) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL2244813 | 0.80 | CYP17A1 (0.58) | CYP17A1DRD2MAPK14NAMPTPSMB8 | |
| SCHEMBL14270301 | 0.80 | AOC3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254085-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-08-01 | — | — | US | disclosed |
| EP-4334290-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | The University of British Columbia (CA) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022232943-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022232943-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254085-A1 | CHELATORS FOR RADIOMETALS AND METHODS OF MAKING AND USING SAME | RXFP3, SLC39A3, NR4A3 | CYP17A1 1588/4885DRD2 2085/4885MAPK14 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.