SCHEMBL247242

SCHEMBL247242

COC([O])(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17729854 0.78
SCHEMBL6755070 0.75
SCHEMBL2460678 0.72
SCHEMBL16668858 0.72
SCHEMBL2460676 0.72
SCHEMBL17729837 0.70
SCHEMBL10463 0.70
SCHEMBL15534574 0.70
SCHEMBL17729846 0.70
SCHEMBL21487697 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3539956-A1 METHOD FOR PRODUCING CHIRAL 8- (3-AMINO-PIPERIDIN-1-YL) -XANTHINES Boehringer Ingelheim International GmbH (DE) 2019-09-18 EP claimed
EP-3029040-B1 METHOD FOR PRODUCING CHIRAL 8-(3-AMINO-PIPERIDIN-1-YL) -XANTHINES BOEHRINGER INGELHEIM INT (DE) 2019-04-03 EP claimed
EP-3029040-A1 METHOD FOR PRODUCING CHIRAL 8- (3-AMINO-PIPERIDIN-1-YL) -XANTHINES Boehringer Ingelheim International GmbH (DE) 2016-06-08 EP claimed
EP-2287164-B9 Process for the manufacture of chiral 8-(3-aminopiperidin-1-yl)-xanthines BOEHRINGER INGELHEIM INT (DE) 2014-06-11 EP claimed
EP-2287164-B1 Process for the manufacture of chiral 8-(3-aminopiperidin-1-yl)-xanthines BOEHRINGER INGELHEIM INT (DE) 2014-01-22 EP claimed
US-7423046-B2 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors NYCOMED GMBH (DE) 2008-09-09 US claimed
JP-2008519005-A 2008-06-05 JP claimed
EP-1812438-A1 METHOD FOR PRODUCING CHIRAL 8-(3-AMINO-PIPERIDIN-1-YL)-XANTHINES Boehringer Ingelheim International GmbH (DE) 2007-08-01 EP claimed
WO-2006048427-A1 METHOD FOR PRODUCING CHIRAL 8-(3-AMINO-PIPERIDIN-1-YL)-XANTHINES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-05-11 WO claimed
EP-0122231-B1 HERBICIDAL AGENT CIBA-GEIGY AG (CH) 1990-01-17 EP claimed
WO-2024084360-A1 PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 (PNPLA3) MODIFIERS PFIZER INC. (US) 2024-04-25 WO disclosed
WO-2024084363-A1 USE OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 COMPOUNDS PFIZER INC. (US) 2024-04-25 WO disclosed
US-20240025883-A1 PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2024-01-25 US disclosed
WO-2024017856-A1 NOVEL ISOQUINOLINONE, PYRROLOPYRIDINONE AND THIENOPYRIDINONE SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2024-01-25 WO disclosed
EP-4298092-A1 NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2024-01-03 EP disclosed
EP-2174934-A1 OXOPYRAZINE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-04-14 EP disclosed
EP-1982978-A1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-22 EP disclosed
US-20070203181-A1 Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient MEIJI SEIKA KAISHA, LTD. (JP) 2007-08-30 US disclosed
EP-1780202-A1 QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT MEIJI SEIKA KAISHA LTD. (JP) 2007-05-02 EP disclosed
US-20050266422-A1 Fluoroalkoxy, nucleosides, nucleotides, and polynucleotides SIRNA THERAPEUTICS, INC. (US) 2005-12-01 US disclosed