Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 6/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003905 | 1.00 | KCNJ1 (0.52) | KCNJ1HRH3TSHRLMNAMAPT | |
| SCHEMBL24775079 | 0.78 | TSHR (0.49) | KCNJ1TSHRMAPTKMT2A | |
| SCHEMBL9108667 | 0.77 | MAPT (0.39) | KCNJ1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL15653751 | 0.76 | KCNJ1 (0.55) | KCNJ1HRH3TSHRLMNAMAPT | |
| SCHEMBL30751818 | 0.74 | KCNJ1 (0.48) | KCNJ1KMT2A | |
| SCHEMBL24668346 | 0.74 | MAPT (0.64) | KCNJ1HRH3LMNAMAPTUBE2T | |
| SCHEMBL24724304 | 0.73 | OGA (0.39) | KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL24724303 | 0.73 | KCNJ1 (0.56) | KCNJ1HRH3TSHRLMNAMAPT | |
| SCHEMBL30004713 | 0.73 | KCNJ1 (0.56) | KCNJ1HRH3TSHRLMNAMAPT | |
| SCHEMBL3595779 | 0.72 | KCNJ1 (0.55) | KCNJ1HRH3TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253259-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |