Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856748 | 0.64 | SMN1; SMN2 (0.33) | ALDH1A1 | |
| SCHEMBL24780441 | 0.64 | SMN1; SMN2 (0.33) | ALDH1A1 | |
| SCHEMBL13992911 | 0.63 | TP53 (0.33) | — | |
| SCHEMBL12191585 | 0.60 | — | — | |
| SCHEMBL4829865 | 0.60 | — | — | |
| SCHEMBL30663809 | 0.60 | — | — | |
| SCHEMBL12994703 | 0.60 | — | — | |
| SCHEMBL31517936 | 0.59 | — | — | |
| SCHEMBL1902505 | 0.57 | — | — | |
| SCHEMBL24780953 | 0.57 | BACE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256676-A1 | SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-12-08 | — | — | WO | disclosed |